TP方案联合唑来膦酸治疗肺腺癌骨转移的疗效分析

Curative Effect Analysis of TP Program Combined with Zoledronic Acid Treatment in Pulmonary Adenocarcinoma with Bony Metastasis Therapy

目的:观察TP化疗方案联合唑来膦酸治疗肺腺癌骨转移的疗效。方法:把52例骨转移的肺腺癌患者随机分为两组,治疗组30例,对照组22例。治疗组接受唑来膦酸联合TP方案化疗,对照组为单纯TP方案化疗。结果:治疗组疼痛缓解率80.0%,对照组45.4%(x^2=6.69,P<0.05);骨病灶控制总有效率,治疗组为53.3%,对照组为22.7%(x^2=4.93,P<0.05)。两组均无明显的不良反应。结论:唑来膦酸联合TP方案化疗对肺腺癌骨转移有较好的治疗作用。

Objective：To observed efficacy of TP program combined with zoledronic acid treatment in pulmonary adenocarcinoma bony metastasis therapy.Methods：Divided 52 patients with pulmonary adenocarcinoma bony metastasis into two groups,Treatment group 30 cases,Control group 22 eases.The treatment group received zoledronic acid combined with TP Program.Control group,TP program alone. Results：Treatment group, 80.0% rate of pain relief, Control group,45.4% （X^2=6.69,P〈0.05）;the total control effective rate of bone lesions,Treatment group,53.3%,control group,22.7%（X^2=4.93,P〈0.05）.There were no obvious adverse reactions.Conclusion：TP program combined with zoledronic acid treatment in pulmonary adenocarcinoma with bony metastasis have better therapeutic effect.