盐酸戊乙奎醚与阿托品治疗有机磷农药中毒疗效对比分析

Penehyclidine Hydrochloride and Atropine Treatment of Organophosphorus Pesticide Poisoning Compare the Effect

目的:通过观察了解新型抗胆碱药长托宁在有机磷农药中毒中的疗效。方法:随机将89例有机磷农药中毒患者分为治疗组和对照组各为47例和42例,治疗组用长托宁、对照组用阿托品,两者均配伍用氯磷定。结果:两组给药的次数和总量、不良反应、ChE恢复时间、治愈率、住院天数等差异均具有统计学意义。结论:长托宁治疗有机磷农药中毒用药剂量小,不良反应少,比阿托品更加有效方便。

Objective： To study the efficacy of penehyclidine on cases of organophosphorus pesticide poisoning.Methods： 89cases of the patients with organophsphorus pesticide poisoning were randomly divided into therapeutic group and control group.47 cases in therapeutic group were treated with penehyclidine and 42 cases in control group with atropine both of compatibility with pralidoxine chloride.Results： The times giving drugs and lotal dosage,adverse reactions, ChE recovery time, cure rate of hospitalization days and so the differences were statistically significant.Conclusions： penehyclidine treatment of organoohosohorus oesticide poisoning dosage is small,fewer adverse reaction than the ateopine is more effective,more convernient.