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维生素E对体外培养人成纤维细胞基质金属蛋白酶-12及赖氨酸氧化酶基因表达的影响

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摘要 维生素E(VitE)是体内最重要的脂溶性抗氧化剂之一,其主要生物学功能是将脂质过氧化自由基还原成脂质过氧化物,从而阻止分子氧和自由基通过非酶反应对不饱和脂肪酸的氧化。有报道表明,部分基质金属蛋白酶(MMPs)的上调可使真皮胶原和弹性蛋白降解增加,基质金属蛋白酶-12(MMP-12)可以降解弹性蛋白,
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2010年第1期12-14,共3页 Journal of Clinical Dermatology
基金 天津市自然科学基金资助项目(003610211)
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参考文献9

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