摘要
Objective：To study the clinical effect of Chinese drugs administered by both oral intake and retention enema on inflammatory bowel diseases（IBD）.Methods：Adopting a randomized controlled design,78 patients were assigned to three groups：26 patients in group A treated with Chinese drugs given by both oral intake and retention enema,27 in group B with Chinese drugs given by retention enema only,and 25 in group C with given Western medicine.The changes before and after a 30-day treatment of the patients＇ symptoms （including diarrhea,abdominal pain,mucous or pus-bloody stool）,colonoscopic examination scores and histopathology of the colonic membrane were observed.Results：Group A showed the best outcomes in all the aspects of clinical comprehensive effectiveness.Improvements in the main symptoms,colonoscopic scores and histopathology of the colonic membrane were significantly different from those in groups B and C,respectively （P〈0.05）.Meanwhile comparisons between groups B and C showed insignificant differences（P〉0.05）; group B was better in ameliorating tenesmus（P〈0.05）.Conclusion：Through the use of Chinese drugs administered by both oral intake and retention enema to treat IBD,which combined external-internal therapies for both overall regulation and local managment,it was confirmed that the Chinese medicine could embody the therapeutic principle of attending to both disease-diagnosis and syndrome-differentiation.
Objective：To study the clinical effect of Chinese drugs administered by both oral intake and retention enema on inflammatory bowel diseases（IBD）.Methods：Adopting a randomized controlled design,78 patients were assigned to three groups：26 patients in group A treated with Chinese drugs given by both oral intake and retention enema,27 in group B with Chinese drugs given by retention enema only,and 25 in group C with given Western medicine.The changes before and after a 30-day treatment of the patients＇ symptoms （including diarrhea,abdominal pain,mucous or pus-bloody stool）,colonoscopic examination scores and histopathology of the colonic membrane were observed.Results：Group A showed the best outcomes in all the aspects of clinical comprehensive effectiveness.Improvements in the main symptoms,colonoscopic scores and histopathology of the colonic membrane were significantly different from those in groups B and C,respectively （P〈0.05）.Meanwhile comparisons between groups B and C showed insignificant differences（P〉0.05）; group B was better in ameliorating tenesmus（P〈0.05）.Conclusion：Through the use of Chinese drugs administered by both oral intake and retention enema to treat IBD,which combined external-internal therapies for both overall regulation and local managment,it was confirmed that the Chinese medicine could embody the therapeutic principle of attending to both disease-diagnosis and syndrome-differentiation.
基金
Supported by Heilongjiang Administration of Traditional Chinese Medicine
