红蓝光照射结合系统服药治疗中重度痤疮261例疗效观察

Observation of combination treatment on 261 patients with medium severe acne and red-blue LED phototheraphy

目的:利用药物和红蓝光结合的方法治疗中重度痤疮,评估治疗方法的疗效和安全性。方法:选取我院痤疮门诊患者中490例评分较高的中重度痤疮患者作为观察对象,对照组(229例)给予药物治疗,治疗组(261例)在药物治疗基础上结合红蓝光治疗,疗程4～6周,详细评分、记录,采用SPSS13.00软件对数据进行统计学分析。结果:两组患者经治疗后,治疗组痤疮皮损均有所减轻,治疗前后有显著性差异(P<0.0l);治疗组患者有效率94.63%,对照组有效率81.66%,治疗组有效率显著高于对照组(P<0.05)。结论:系统服药结合红蓝光等物理方法治疗中重度痤疮安全、有效,可明显缩短疗程,减少痤疮后遗留瘢痕,值得临床借鉴和推广应用。

Objective To investigate the combination therapy in patients of acne.Methods 490 patients with medium to severe acne were divided into two groups randomly：control group（229 cases） and treated group（261 cases）.Both two groups were divided into five categories by different symptoms,the cases in treated group had been treated with drugs and red-blue light-emitting diode-based system for four to six weeks,as the cases in control group were treated with drug only.The data in both groups were analyzed statistically.Results A mean reduction in lesion count was observed,statistically significance differences in effectiveness were found among each group（P〈0.01）,the effective ratio was 94.63% in treated group,of which was 81.66% in control group,it showed significant difference between these two groups（P〈0.05）.Conclusion Specifically red-blue light has a marked effect on inflammatory acne lessions,and the treatment with drugs plus red-blue light radiation therapy appears to have excellent potential in the treatment of medium to severe acne.