广州市天河区2006-2008年孕产妇梅毒感染状况调查

Survey of Syphilis Infection among Pregnant Women in Tianhe District of Guangzhou City from 2006 to 2008

目的了解天河区孕产妇梅毒感染状况,为梅毒防治决策提供依据。方法对2006-2008年在本院产科门诊产检的孕妇10754例,采用TRUST作梅毒抗体初筛试验,采用TPPA作梅毒抗体确认试验。结果广州市天河区孕妇梅毒感染率逐年上升,其中2006年3012例孕妇梅毒感染率为1.39%,2007年3727例孕妇梅毒感染率为2.20%,2008年4015例孕妇梅毒感染率为2.81%。不同年龄组孕产妇梅毒阳性率差异无统计学意义(χ2=0.0415,P>0.05);不同职业的孕产妇梅毒阳性率差异有统计学意义(χ2=120.453,P<0.05);不同文化程度的孕产妇梅毒阳性率差异有统计学意义(χ2=47.52,P<0.05)。结论对孕妇进行梅毒血清学检测及规范治疗是杜绝先天梅毒、切断母婴垂直传播的有效方法和措施。

Objective To provide evidence for the decision-making of syphilis prevention through studying on the prevalence of maternal syphilis in Tianhe district.Methods Pregnant women visiting our obstetrics clinic for prenatal examination between 2006 and 2008 were screened for infection.Toluidine Red Unheated Serum Test （TRUST） was used in the initial screening of syphilis. Treponemal Pallidum Particle Agglutination （TPPA） was used as the confirm test.Results The syphilis infection rate of pregnant woman in the Guangzhou Tianhe district was increasing between 2006 and 2008. In 2006, the syphilis infection rate of 3 012 pregnant woman was 1.39%.In 2007, the infection rate of 3 727 pregnant woman was 2.20%.In 2008,the infection rate of 4 015 pregnant woman was 2.81%.The infection rate in each age group was similar （χ^2=0.0415,P〉0.05）.The increase in infection rate was correlated with the occupation （χ^2=120.453,P〈0.05） and also their level of education （χ^2=47.52,P〈0.05）. Conclusion Serological screening of syphilis in pregnant women is effective in reducing the incidence of congenital syphilis and prevent the vertical transmission of syphilis to the infants.