酵母细胞凋亡研究进展

Apoptosis in yeast

细胞凋亡是调节生物体正常发育和生命活动的一种不可缺少的机制,其研究生命力在于最终能够有利于疾病机制的阐明以及新疗法的探索及问世。酵母细胞由于凋亡过程的高度保守性及其作为分子生物学模式物种的先天优势,近年来一直是凋亡研究的热点。目前对酵母细胞凋亡的核心分子、传导通路和诱因等已经有了深入的了解。

Apoptosis can be defined as a highly regulated cellular suicide program which is crucial for development of organism.Yeast is popular for apotosis reseach because of the highly conservative nature and the superiority as model species of molecular biology.This review focuses on the core components,pathway and incentives of yeast apoptosis.