他扎罗汀乳膏(乐为)治疗寻常型痤疮的临床疗效观察

Efficacy of Tazarotene Cream in the Treatment of Acne Vulgaris

目的:观察0.1%他扎罗汀乳膏(乐为)治疗寻常型痤疮的临床疗效和安全性。方法:以轻中度痤疮患者40例,随机分为治疗组20例,外用0.1%他扎罗汀乳膏每晚1次,连用4周;对照组20例,外用0.1%维A酸霜每晚1次,连用4周,停药后观察疗效。结果:治疗组基愈8例,显效7例,总有效率75%;对照组基愈5例,显效6例,总有效率55%。两组结果经统计学处理,差异有显著性,P<0.05。结论:他扎罗汀乳膏治疗寻常型痤疮安全、有效。

Objective：To evaluate the efficacy and safety of 0.1% Tazarotene Cream （Tazhaluoting Rugao）in the treatment of acne vulgaris.Methods：40 patients,diagnosed clinically to have mild to moderate acne vulgaris were randomly and averagely assigned to two groups.0.1% Tazarotene Cream and 0.1%Tretinoin Cream were used respectively daily night for 4 weeks on these two groups.Observe the efficacy after the ointment withdrawal.Results：8 patients were basically cured and 7 improved in the experiment group,the total effective rate was 75.0%.5 patients were basically cured and 6 improved in the control group,the total effective rate was 55.0%.There is significant difference between these two groups statistically （P〈0.05）.Conclusion：Tazarotene Cream is quite effective and safe in the treatment of acne vulgaris.