摘要
目的:探讨2型糖尿病合并糖尿病足患者与胰岛素抵抗的关系。方法:205例2型糖尿病患伴糖尿病足患者作为观察组,无足部病变的糖尿病患者作为对照组,观察其体重指数、空腹血糖、胰岛素、血脂等指标,两组间进行比较并相关性分析、多元回归分析。胰岛素抵抗指数(HOMA-IR)=FPG×FIns/22.5。结果:糖尿病足患者的HOMA-IR显著高于无糖尿病的患者(P<0.05)。多元回归分析显示糖尿病病程、LDL及BMI是影响2型糖尿病足患者胰岛素抵抗的主要危险因素。结论:糖尿病足患者存在着更严重的胰岛素抵抗。
Objective:To discuss the relationship between diabetes and pedopathy of typeⅡdiabetes and insulin resistance. Methods:The diabetes typeⅡpatients were divided into group A(combined with pedopathy) and group B (without pedopathy).The blood glucose and insulin of empty stomach,BMI,Alc and lipid were detected.The insulin resistance index(HOMA-IR) was calculated and compared between two groups.Results:The HOMA-IR was higher in group A than that in group B(P0.05).The duration of disease,LDL and BMI was positive related with diabetes pedopathy.Conclusion:The insulin resistance was more worse in pedopathy of TypeⅡdiabetes.
出处
《华西医学》
CAS
2009年第11期2905-2906,共2页
West China Medical Journal
关键词
2型糖尿病
糖尿病足
胰岛素抵抗
typeⅡdiabetes
diabetes pedopathy
insulin resistance