摘要
目的:探讨2型糖尿病合并糖尿病足患者与胰岛素抵抗的关系。方法:205例2型糖尿病患伴糖尿病足患者作为观察组,无足部病变的糖尿病患者作为对照组,观察其体重指数、空腹血糖、胰岛素、血脂等指标,两组间进行比较并相关性分析、多元回归分析。胰岛素抵抗指数(HOMA-IR)=FPG×FIns/22.5。结果:糖尿病足患者的HOMA-IR显著高于无糖尿病的患者(P<0.05)。多元回归分析显示糖尿病病程、LDL及BMI是影响2型糖尿病足患者胰岛素抵抗的主要危险因素。结论:糖尿病足患者存在着更严重的胰岛素抵抗。
Objective：To discuss the relationship between diabetes and pedopathy of typeⅡdiabetes and insulin resistance. Methods：The diabetes typeⅡpatients were divided into group A（combined with pedopathy） and group B （without pedopathy）.The blood glucose and insulin of empty stomach,BMI,Alc and lipid were detected.The insulin resistance index（HOMA-IR） was calculated and compared between two groups.Results：The HOMA-IR was higher in group A than that in group B（P0.05）.The duration of disease,LDL and BMI was positive related with diabetes pedopathy.Conclusion：The insulin resistance was more worse in pedopathy of TypeⅡdiabetes.
出处
《华西医学》
CAS
2009年第11期2905-2906,共2页
West China Medical Journal
关键词
2型糖尿病
糖尿病足
胰岛素抵抗
typeⅡdiabetes
diabetes pedopathy
insulin resistance
