实验动物臂丛神经的拉伸力学特性

Tensile mechanical properties of the brachial plexus of experimental animals

背景：臂丛神经损伤缝合吻接术有必要了解臂丛神经拉伸力学特性。目的：对大鼠臂丛神经进行拉伸实验,观察其臂丛神经的拉伸力学特性,为临床提供拉伸力学特性参数。方法：取SD大鼠C6~7臂丛神经40个,随机分为正常对照组20个,模拟臂丛神经损伤吻接组20个,对模拟臂丛神经损伤吻接组以手术刀在标本中间切开再缝合吻接离断标本。在电子万能试验机上以5mm/min的实验速度对2组标本进行拉伸实验,以多项式用最小二乘法处理实验数据。拉伸实验速度为5mm/min。观察大鼠臂丛神经拉伸最大载荷、最大位移、最大应变、最大应力和应力-应变曲线。结果与结论：模拟臂丛神经损伤吻接组大鼠臂丛神经拉伸最大载荷为（1.050±0.135）N、最大位移为（3.090±0.356）mm、最大应变为（61.860±7.252）%、最大应力为（5.095±0.647）GPa,正常对照组最大载荷、最大应力大于模拟丛神经损伤吻接组（P〈0.05）。模拟臂丛神经损伤吻接组最大位移和最大应变大于正常对照组（P〈0.05）。拉伸应力-应变曲线是以指数关系变化的。结果显示2组臂丛神经标本具有不同的拉伸力学特性。

BACKGROUND： It is necessary to understand the brachial plexus stretch mechanical properties for the brachial plexus injuries suture anastomosis technique. OBJECTIVE： The brachial plexus of laboratory animals was performed tensile experiment to observe the tensile mechanical properties, which can provide the tensile mechanical properties parameters for the clinic. METHODS： A total of 40 C6-7 brachial plexus of rats were obtained and randomly divided into the normal control group （n = 20） and analog brachial plexus injury anastomosis group （n = 20）. The middle of the specimen was cut off from the broken suture by hand-cut way to the analog brachial plexus injury anastomosis. Tensile test with the speed of 5 mm/min was performed, and the experimental data was treated by using the polynomial and Least-squares method. The tensile maximum load, maximum displacement, maximum strain, maximum stress, and stress-strain curve were observed. RESULTS AND CONCLUSION： The tensile maximum load of the analog brachial plexus injury anastomosis group was （1.050±0.135） N, maximum displacement was （3.090±0.356） mm, maximum strain was （61.860±7.252）%, and maximum stress was （5.095±0.647） MPa. The tensile maximum load and the maximum stress of the normal control group were greater than those of the analog brachial plexus injury anastomosis group （P 0.05）, but the maximum displacement and maximum strain were smaller than the analog brachial plexus injury anastomosis group （P 0.05）. The tensile stress-strain curve is changed in exponential relationship. The results demonstrated that the two groups of brachial plexus tensile specimens have different mechanical properties.