胰岛素泵治疗糖尿病合并感染患者的临床疗效

Clinical Application of Insulin Pump in Infected Patients with Diabetes

[目的]探讨胰岛素泵治疗在糖尿病合并感染治疗中的效果及安全性.[方法]糖尿病合并感染患者68例,分为两组：胰岛素泵持续皮下输注治疗36例（CSII组）,多次胰岛素皮下注射治疗32例（MSII组）.比较两组患者治疗后血糖变化及血糖达标时间、胰岛素用量、低血糖发生率、住院总天数等的差异.[结果]治疗后两组患者血糖均明显下降（P〈0.01）,CSII组对空腹血糖的控制优于MSII组（P〈0.05）,血糖达标时间、胰岛素用量、低血糖发生率均低于MSII组（P〈0.01,P〈0.05）.[结论]在糖尿病合并感染患者应用胰岛素泵治疗可迅速控制血糖,缩短血糖达标时间,减少低血糖的发生.

[Objective] To evaluate the efficacy and safety of insulin pump in the treatment of infected patients with diabetes. [Methods] Sixty eight infected patients with diabetes were divided into continuous subcutaneous insulin infusion （CSII） group （ n = 36） and multiple subcutaneous insulin infusion （MSII） group （ n = 32）. The level of blood glucose, the spending time when blood glucose fell to achieve better standards, dosage of insulin, incidence of hypoglycemia and the hospitalization day were compared between two groups. [Results] The blood glucose significantly decreased in both groups （ P 〈0.01）. The control of fasting plasma glucose of CSII group was superior to MSII group（ P 〈0.05）. The spending time when blood glucose fell to achieve better standards, insulin dosage, the hospitalization day and incidence of hypoglycemia in CSII group were less than those in MSII group （ P〈0. 01, P 〈0. 05）. [Conclusion] Insulin pump is safe and effective for the treatment of infected patients with diabetes. It can control blood glucose quickly, reduce the spending time When blood glucose falls to achieve better standards, and decrease the incidence of hypoglycemia.