食管静脉曲张套扎术后早期出血180例临床分析

Clinical Study on Early Bleeding after Endoscopic Esophageal Variceal Ligation

[目的]分析内镜下食管静脉曲张套扎术（EVL）术后早期出血的发病特点,并探讨预防应用奥曲肽能否有效的减低EVL术后早期出血率、出血量.[方法]回顾性研究180例行EVL治疗患者.术后早期出血的好发时间、诱因、出血量及奥曲肽治疗其的影响.[结果]180例患者,早期出血11例,出血率为6.11%.用药组EVL术后早期出血6例;未用药组5例.出血时间集中在术后d7～14,达72.73%.两组患者出血率及出血量无明显差异.[结论]EVL术后早期出血发病特点为术后早期出血率低,但出血量大.术后d7～14是EVL术后早期出血的好发时间.预防应用奥曲肽并不能降低EVL术后早期出血率、出血量.

[Objective]To study the characteristics of the early bleeding after endoscopic esophageal ligation（EVL） and to explore if octreotide can decrease the incidence of early bleeding and the amount of bleeding. [Methods]One hundred eighty patients who underwent EVL were analyzed retrospectively. The early bleeding rate after EVL was determined. The onset, predisposition factors and the amount of bleeding were observed. The effect of octreotide on early bleeding rate and the amount of bleeding was studied. [Results]The bleeding rate was 6.11 % （11/180）. Bleeding occurred in 6 patients in octreotide treatment group and 5 in control group after EVL. Early bleeding mostly occurred in the first 7~14 days after EVL（72.73%）.. There was no significant difference in the bleeding rate and the amount of bleeding between oetreotide treatment group and control group（ P 〉0.05）. [Conclusion] Early bleeding rate is low but the bleeding is massive after EVL.. Prophylactic administration of octreotide does not reduce the early bleeding and its amount after EVL.