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D-二聚体与急性肺栓塞预后的关系 被引量:3

Relationship Between D-dimer levels and Prognosis in Acute Pulmonary Embolism Patients
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摘要 [目的]研究D-二聚体(D-D)对1年内的肺栓塞的复发率和病死率的预测价值.[方法]测定71例肺栓塞患者血浆中D-D.并进行1年随访,了解是否出现复发或死亡.[结果]病情程度不同各组间D-D水平有显著性差异(P〈0.001).直线相关分析显示D-D与复发率和病死率呈独立负相关关系(r=-0.613,P〈0.001) .[结论]D-二聚体水平可以作为急性肺栓塞预后的预测指标. [Objective]To explore the value of D-dimer(fibrin degradation product) for predicting the recurrence and mortality of pulmonary embolism in a year. [Methods] A total of 71 patients with pulmonary embolism were enrolled. All patients were divided into 4 groups. Plasma D-dimer was measured by automatic immuno-analytical system VDAS DD assay. Suspect pulmonary embolism patients were followed up for a year in order to understand the recurrence and mortality rate. [Results]The differences in D-dimer levels among these groups were significant ( P d0. 001). The linear correlation analysis showed that D-dimer was negatively independently related with the recurrence and mortality rate(r=-0. 613 , P 〈0. 001). [Conclusion] D-dimer level can be considered as a potential predictive index for the prognosis of acute pulmonary embolism.
出处 《医学临床研究》 CAS 2010年第5期893-895,共3页 Journal of Clinical Research
关键词 肺栓塞 纤维蛋白纤维蛋白原降解物 预后 pulmonary embolism fibrin fibrinogen degradation products prognosis
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