紫外线红斑对犬皮下瘀血作用的实验研究

Experimental study of ultraviolet erythema on subcutaneous ecchymosis in dogs

目的：进一步探讨紫外线（ＵＶ）照射治疗皮下瘀血的作用机制。方法：复制犬皮下瘀血模型后，观察瘀血区ＵＶ红斑、血纤溶活性（ＦＳ）的变化对犬瘀血吸收时间的影响。结果：ＵＶ照射可激活犬血ＦＳ，但照射区瘀血斑无明显变化；在抑制ＵＶ照射对犬血ＦＳ的激活条件下，ＵＶ照后瘀血斑吸收时间无统计学意义的变化（Ｐ＞００５）；瘀血区ＵＶ红斑减弱后其瘀血平均吸收时间显著延长（Ｐ＜００１）。结论：红斑效应为ＵＶ照射治疗后犬皮下瘀血的机制。

Objective:To elucidate the mechanism of ultraviolet(UV) radiation on subcutaneous ecchymosis.Methods:After replicating the subcutaneous ecchymosis models of dogs,the ecchymosis was radiated with UV erythema to observe the alteration of blood fibrinolytic system and the duration of ecchymosis absorption.Results:After UV radiation,the blood fibrinolytic system was activated,there wasn't changed without UV radiation dogs.If the UV erythema was inhibited or decreased,the ecchymosis absorption was also delayed.Conclusion:The finding shows that the mechanism of UV radiation to ecchymosis is mainly the UV erythema reaction.