保定市普通人群丙型肝炎病毒感染的调查

Detection of the positive rate of serum hepatitis C virus antibody in Boding region and its clinical significance

目的探讨保定市普通人群丙型肝炎病毒(hepatitis Cvirus,HCV)感染率,观察HCV感染趋势。方法用酶联免疫吸附试验(ELISA法)检测2006年至2008年保定市普通人群血清中抗-HCV。结果 2006年至2008年保定市普通人群抗-HCV阳性率依次为0.47%、0.48%和0.49%,呈轻微上升趋势。结论输血及静脉吸毒是HCV主要传播方式,对有过受血(血制品)史、静脉吸毒史、职业暴露史以及有血液透析、手术、拔牙、针刺纹身等经历的人员,实行抗-HCV筛检显得尤为重要。

Objective To investigate the positive rate of serum anti-HCV and the main mode of t ransmission of HCV in Baoding region ,and evaluate the clinical significance of anti-HCV detection in common people. Methods Enzyme linked immunosorbent assay （ELISA） was applied to detect serum anti-HCV in people in Baoding region from 2006 to 2008;the annual positive rate was recorded ,and the HCV infection tendency was observed. The varia-bility of infection way was investigated through investigating the case history. Results The positive rates of anti -HCV from 2006 to 2008 were 0.46% , 0.47% and 0.48% respectively , displaying a slightly rising trend. Conclusion There is a slightly ascendent tendency in HCV infection in Baoding region from 2006 to 2008 , the situation shouldn′t be despised. Blood transfusion and venous drug taking are the main infection ways. It plays an important role to availably grasp the situation of HCV infection by detecting serum anti-HCV in common people in early diagnosis of hepatitis C and timely prevention of HCV transmission in crowd.