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多基因疾病基因定位的遗传分析方法 被引量:4

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摘要 多基因疾病基因定位的遗传分析方法赵进英,蔡有余,方福德(医学分子生物学国家重点实验室,北京100005)多基因疾病由于存在异质性,基因定位是一件复杂和困难的事情。多基因疾病的基因定位包括实验和数据处理与分析两部分工作,后者更加困难和重要,因为要做好这...
出处 《基础医学与临床》 CSCD 1999年第1期6-9,共4页 Basic and Clinical Medicine
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  • 1Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3,000 shared controls [ J ]. Nature, 2007,447(7145) :661-678.
  • 2MePherson R, Pertsemlidis A, Kavaslar N, et al. A common allele on chromosome 9 associated with coronary heart disease [ J ]. Science, 2007,316 (5830) : 1488-1491.
  • 3Helgadottir A,Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction [ J ]. Science, 2007,316 (5830) :1491-1493.
  • 4Samani N J, Erdmann J, Hall AS, et al. Genomewide association analysis of coronary artery disease[J]. N Engl J Med,2007,357(5) :443-453.
  • 5Kathiresan S, Voight BF, Purcell S, et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants[J]. Nat Genet,2009,41 (3) :334-341.
  • 6Rosenzweig A. Scanning the genome for coronary risk[ J]. N Engl J Med,2007, 357 (5) :497-499.
  • 7Slagboom PE, Heijmans BT, Beekman M, et al. Molecular epidemiology, candidate genes versus genome-wide scansv [ J ]. Genes Nutr,2007,2 ( 1 ) :27-29.
  • 8Farzaneh-Far R, Na B, Schiller NB, et al. Lack of association of chromosome 9p21.3 genotype with cardiovascular structure and function in persons with stable coronary artery disease : The Heart and Soul Study [ J ]. Atherosclerosis, 2008,205 ( 2 ) :492-496.
  • 9Summaries for patients. Does measuring genetic variations at chromosome9p21.3 help to predict cardiovascular disease in women [ J ] ? Ann Intern Med,2009,150(2) :1-36.
  • 10Bjorck HM, Lanne T, Alehagen U, et al. Association of genetic variation on chromosome 9p21.3 and arterial stiffness [ J ]. J Intern Med, 2009,265 ( 3 ) : 373-381.

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