239例麻疹流行特征和临床分析

The epidemiology and clinical analysis on 239 measles cases

目的探讨2008年度麻疹流行病学特征及临床特点。方法对本院收治的239例麻疹患者的临床资料进行回顾分析。结果239例患者(男126例,女113例),男女比为1.12:1,平均年龄29.4岁,非本市户籍人员占37.66%,发病集中于4月～5月,血清麻疹病毒IgM抗体阳性率为74.1%;热峰高于39℃者197例(82.43%),并发急性支气管炎者43例(17.99%),并发支气管肺炎者23例(9.62%),并发急性喉炎者26例(10.88%),并发肝损伤者149例(62.34%)。结论麻疹患者可能与麻疹疫苗接种不规范或接种疫苗抗体滴度下降等因素有关,临床特征具有较重的病毒血症以及肝脏损伤。

Objective To study the epidemiology and clinical feature of measles in 2008.Methods Retrospective survey and analysis were carried out on 239 measles cases.Results All 239 patients （including 126 males and 113 females）,the male and female ratio was 1.12∶1,average age was 29.4 years old and the out-of-towner accounts 37.66%.The morbidity concentrates in April and May.Among all the cases,74.1% were serum IgM positive,temperature higher than 39℃ accounted 82.43%,cases complicated by acute bronchitis,bronchopneumonia,acute laryngitis and liver damage were 43 cases （17.99%）,23 cases （9.62%）,26 cases （10.88%） and 149 cases （62.34%）,respectively.Conclusions Measles is probably related to irregular vaccination or antibody level drop,with the clinical feature of heavy viremia as well as liver damage.