老年慢性细菌性前列腺炎病原菌分布及耐药性分析

Distribution and Drug Resistance of Pathogens Caused Chronic Bacterial Prostatitis

目的探讨老年慢性细菌性前列腺炎的病原菌分布与耐药性,为临床提供疾病诊断及治疗依据。方法采集老年慢性前列腺炎患者的前列腺液进行细菌培养和体外药敏试验,并进行统计分析。结果 316例老年慢性前列腺炎患者的前列腺液中共检出病原菌205株,其中革兰阳性菌123株,占60.0%;以金黄色葡萄球菌为主。革兰阴性菌82株,占40.0%;以大肠埃希菌为主。前列腺炎病原菌对常用抗菌药物已产生了耐药性,检出耐甲氧西林葡萄球菌(MRS)35株,占葡萄球菌属总数的34.7%;产ESBLs病原菌占肠杆菌科细菌总数的35.6%。结论老年慢性细菌性前列腺炎具有难治性和迁延性,应加强病原菌耐药性检测,提高治愈率。

[Objective]To investigate the distribution and drug resistance of pathogens caused chronic bacterial prostatitis,and provide evidence for clinical diagnosis and treatment.[Methods]Prostatic fluid from the senile patients with chronic bacterial prostatitis was collected for bacterial cultures and in vitro drug sensitive test.The data were analyzed statistically.[Results]Of 316 senile patients with chronic bacterial prostatitis,205 isolates of pathogens were detected,among which 123 were Gram-positive,accounting for 60.0%;most were Staphylococcus aureus.82 isolates were Gram-negative,accounting for 40.0%;most were Escherichia coli.Pathogens causing prostatitis had been resistant to the common antibiotics,among the total staphylococci,meticillin-resistant Staphylococcus aureus（MRS） accounted for 34.7%（35 isolates）,and among the total Enterobacteriaceae,ESBLs prodacing bacterial accounted for 35.6%.[Conclusion]Chronic bacterial prostatitis in the senile patients possesses intractability and persisting.The drug-resistance detection of pathogens should be strengthened to improve the cure rate.