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无铜(Ⅰ)催化的点击化学 被引量：3

Copper-free Click Chemistry
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摘要 铜催化的点击化学由于其潜在的毒性,在生物学系统中已被排除在外,因此越来越多的研究转向了无金属催化的点击化学。主要介绍了最新无铜(Ⅰ)催化的点击化学(click chemistry)以及与铜(I)催化(CuAAC)的比较。综述了点击化学在无铜催化下作为一种快速、稳健、高效的方法在合成上的一些应用,并对其发展前景进行了展望。 The copper-catalyzed click chemistry was precluded in the applications of biological systems due to its inherently toxicity.An increasing number of studies were paid attention to metal-free catalyst systems.As a rapid,robust and efficient synthetic method,some new chemistry under copper-free ＇click＇ was introduced and compared to the CuAAC.At last,future trends of click chemistry under copper-free catalyzed was prospected.
作者 张慧梓 徐佳佳 李耀宗 王锐
机构地区 云南民族大学化学与生物技术学院
出处 《化工时刊》 CAS 2010年第5期58-66,共9页 Chemical Industry Times
关键词 点击化学 无铜(Ⅰ)催化 合成 click chemistry copper-free synthesis
分类号 O643.32 [理学—物理化学]
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参考文献49

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二级参考文献40

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化工时刊
2010年 第5期

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