甘露醇脱水疗法与速尿脱水疗法对晚期恶性肿瘤病人止痛效果的比较

Comparison of the pain-relief effects between dehydration therapy by mannitol and frusemide on advanced malignant cancer patients

目的:分析和比较甘露醇脱水疗法和速尿脱水疗法缓解晚期恶性肿瘤病人疼痛的疗效。方法:回顾性比较因疼痛住院的晚期恶性肿瘤病人甘露醇脱水治疗(37例)和速尿脱水治疗(32例)的止痛效果。结果:甘露醇对疼痛的有效缓解率为86.1%,速尿为62.5%,两组间差别具有统计学意义(P<0.05)。结论:甘露醇比速尿止痛效果更为明显,甘露醇脱水治疗对缓解临终病人的疼痛是一种安全、有效、经济、操作便捷的治疗方法,尤其适合基层医疗单位运用。

Objective：To evaluate the effects of pain-relief on patients suffered from advanced malignant cancer by comparing dehydration therapy with mannitol and frusemide.Methods：The clinical data were retrospectively examined in 37 patients undergone mannitol dehydration therapy and 32 with frusemide therapy during their hospital stay.Results：86.1% of the patients responded to mannitol and 62.5% to frusemide.The analgesic effects were different between the two groups（P0.01）.Conclusion：Mannitol dehydration therapy is more effective for pain relief than frusemide and seems safer,more economic,easy to use and favorable to the application in hospitals on community basis.