急性心肌梗死溶栓治疗相关动脉再通对Q-T_(dr)的影响

Effect of thrombolytlc therapy on Infarct-related coronary artery on Q-Tdr, in patients with acute myocardlal Infarction

为探讨急性心肌梗死溶栓治疗相关动脉再通对Q-T_d及其比值(Q-T_(dr))的影响,观察6h内接受溶栓治疗的96例患者,按冠状动脉有无再通分为再通组(n=54)和未通组(n=42).结果未通组Q-T_d(74±18ms)、Q-T_(cd)(81±26ms)、Q-T_(dr)(8.9%±2.7%)非常明显高于再通组(50±12ms、53±14ms、5.1%±1.7%(P<0.01),且伴心室颤动者Q-T_d(96±17ms)、Q-T_(cd)(106±16ms)、Q-T_(dr)(11.9%±0.7%)明显高于不伴心室颤动者(71±15ms、78±28ms、6.9%±2.3%,P<0.01).提示急性心肌梗死溶栓治疗相关动脉再通可改善心肌电稳定性,降低心室颤动发生率.

To study effect of reperfusion on Q -Td and Q -Tdr we observed 96 patients with acute myocardial infarction, who were receiving 6-hour intravenous urokinase. Patients were divided into two groups: reper-fusive group(54 patients) and nonperfusive gmup(42 patients). Findings indicated all higher that Q -Td (74?18ms), Q-Tcd (81 ?26.5ms) and Q-Tdr (8.9% ?.7%)in nonperfusive group than in reperfusive group(50?12ms,53?13.5ms,5.1% ?1.7% , P< 0.0l). Q-Td (96?17ms), Q-Tcd( 106 ?16.5ms) and Q-Tdr(l1.9% ?.7%) were greatly higher than those in patients who underwent Vf(71 ?15ms,78?27.5ms, 6.9% ?.3%, P<0.01) .Findings suggested that reperfusion can improve electric stability of cardie muscles and lower oceur-rence of Vf.