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链霉菌次生代谢中A因子级联调控研究进展

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摘要 A因子、Bld因子在灰色链霉菌(Streptomyces griseus)、天蓝色链霉菌(S.coelicolor)和其它链霉菌及非链霉菌放线菌中广泛存在,在链霉菌及相关放线菌的形态分化和次生代谢调控中有关键作用。A因子通过A因子-Arp-AdpA级联对多种链霉菌的次生代谢和形态分化有促进作用;Bld因子本质为tRNALeu-UUA,通过在翻译水平上调控含UUA密码子基因的表达来促进形态分化和次生代谢,A因子调控级联中的adpA也是Bld因子调控的靶基因之一。
作者 杨红文 谭勇
机构地区 福建省漳州师范学院生物系 华中农业大学农业微生物国家重点实验室 石河子大学药学院
出处 《长江大学学报（自科版）（中旬）》 CAS 2010年第1期74-78,共5页 Journal of Yangtze University(Nature Science Edition)
关键词 链霉菌(Streptomyces) 次生代谢 A因子 Bld因子
分类号 Q935 [生物学—微生物学]
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参考文献29

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二级参考文献39

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长江大学学报（自科版）（中旬）
2010年 第1期

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