摘要
目的探讨胃肠道间质瘤的诊断及预后相关因素。方法采用S-P免疫组化方法标记42例消化道及腹腔胃肠道间质瘤(GISTS)。结果42例GISTS中Des(+)4例(9.5%),SMA(+)14例(33%),Actin(+)12例(28.6%),CD34(+)36例(85.7%),CD117(+)40例(95.2%),S-100(+)12例(28.6%),Ki-67(+)22例(52.4%),bcl-2(+)28例(66.7%)。结论GISTS的诊断CD117阳性率高于CD34,但在诊断中应两者结合以提高诊断率;肿瘤的大小及核分裂的多少是判断良恶性的重要指标,而所有间质瘤具有潜在恶性。
Objective To investigate the gastrointestinal stromal tumor diagnosis and prognosis factors.Methods SP immunohistochemical method mark 42 cases of gastrointestinal tract and abdominal gastrointestinal stromal tumors（GISTS）.Results 42 cases of GISTS Des（＋）4 Li（9.5%）,SMA（＋）14 Li（33%）,Actin（＋）12 Li（28.6%）,CD34（＋）36 Li（85.7%）,CD117（＋）40 Li（95.2%）,S-100（＋）12 Li（28.6%）,Ki-67（＋）22 Li（52.4%）,bcl-2（＋）28 cases（66.7%）.Couclusion GISTS diagnosis CD117-positive rate is higher than CD34,but the diagnosis should be a combination of both to improve the diagnostic rate;tumor size and the amount of nuclear fission is an important indicator to determine benign or malignant,and all potentially malignant GISTS.
出处
《中外医疗》
2010年第11期5-6,8,共3页
China & Foreign Medical Treatment
关键词
胃肠道间质瘤
诊断
预后
免疫组化
Gastrointestinal stromal tumor
Diagnosis
Prognosis
Lmmunohistochemistry
