血管内皮损伤大鼠模型研究进展

Advances in the Research of Vascular Endothelial Injury in Rats Models

血管内皮细胞损伤已成为许多疾病发生发展的基本病理过程。血管内皮损伤模型作为一种研究工具,在探讨内皮损伤机制、保护血管内皮损伤的药物等研究中发挥积极的作用。研究人员为不同实验设计需要,而寻找理想的血管内皮损伤模型是至关重要的。现全面地介绍常用模型,并对其优缺点进行评价。

Vascular endothelial cell injury has become the occurrence and development of the pathological process in many diseases.Vascular endothelial injury model played an active role as one of research tools in studies to explore the mechanism of endothelial injury,drugs of protect vascular endothelial injury.It was essential for the researchers to design experiments for different needs,to find the ideal model of vascular endothelial injury.In this paper,the common models were introduced completely,and their advantages and disadvantages were evaluated.