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灵芝中性三萜类成分的抗肿瘤作用 被引量:34

Inhibition of Tumor Cell Proliferation by a Neutral Triterpenoid Fraction from Ganoderma lucidum
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摘要 从灵芝(Ganoderma lucidum)子实体中分离纯化得到中性三萜部分,经HPLC检测发现主要有8个峰,与灵芝三萜酸性部分的峰基本不重叠。灵芝中性三萜部分对多种肿瘤细胞的增殖有抑制作用,并观察到可诱导肠癌SW620细胞凋亡。 A neutral triterpene fraction (NTF) isolated from Ganoderma lucidum fruit bodies was shown by HPLC to consist of eight major components which differed from the constituents in an acidic triterpenoid fraction (ATF). The NTF inhibited the proliferation of several tumor cell lines and induced apoptotic bodies in SW620 tumor cells.
出处 《食用菌学报》 北大核心 2010年第1期60-64,共5页 Acta Edulis Fungi
基金 上海市科委国际合作项目“灵芝诱导肠癌细胞凋亡的活性成分及作用机制的研究”(编号:044307041)的部分研究内容
关键词 灵芝 灵芝三萜 抗肿瘤 细胞凋亡 Ganoderma lucidum antitumor neutral triterpene apoptosis
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参考文献7

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