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贝那普利与缬沙坦对急性心肌梗死患者心功能影响的临床对比观察 被引量:3

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摘要 目的比较贝那普利与缬沙坦对急性心肌梗死(AMI)患者心功能的影响并评价两药抑制左室重塑的疗效。方法将符合WHO规定的AMI诊断标准的51例患者分为两组,其中缬沙坦组27例、贝那普利组24例,两组均行AMI常规治疗,缬沙坦组加用缬沙坦80mg/d、贝那普利组加用贝那普利10mg/d,疗程3个月。结果 (1)两组患者的症状评分与治疗前比较有显著性差异(P<0.05),而且贝那普利组的症状评分改善情况优于缬沙坦组(P<0.05)。(2)两组患者的LVESV、LVEF和LVMI较治疗前均明显改善,差异有显著性(P<0.05),而且贝那普利组改善情况优于缬沙坦组(P<0.05)。结论贝那普利和缬沙坦均能明显改善左室功能,阻抑左室重塑过程,提高左室收缩的同步性;而且贝那普利的效果优于缬沙坦。
作者 吴琼 陈福凤
出处 《中国医学创新》 CAS 2010年第15期67-68,共2页 Medical Innovation of China
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