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施捷因对脑出血患者血清S-100β蛋白与神经元特异性的影响 被引量：1

Influence of GM-1 on the expression of S-100β protein and NSE in patients with cerebral hemorrhage
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摘要 目的探讨施捷因对脑出血患者血清S-100β蛋白与神经元烯醇化酶(NSE)表达水平的影响。方法采用酶联免疫吸附法对32例脑出血患者起病1、3、7d血清S-100β蛋白与NSE水平进行动态测定。结果脑出血患者血清S-100β蛋白与NSE浓度在起病1、3、7d均显著升高,经施捷因治疗后表达水平明显下降,与脑出血组比较,差异有统计学意义(P<0.01)。结论施捷因可以显著减轻脑出血患者的神经损伤。 Objective To explore the influence of GM-1 on the expression of S-100β protein and NSE in patients with cerebral hemorrhage.Methods The serum S-100β protein and NSE in 32 patients with cerebral hemorrhage were tested by ELISA at 1st,3rd and 7th day after the hemorrhage happened.Results The serum S-100β protein and NSE values at 1st,3rd and 7th day after the hemorrhage occurred were higher than those of GM-1 treated group （P0.01）.Conclusion The serum S-100β protein and NSE test in patients with cerebral hemorrhage are very useful in judging the severity and prognosis.
作者 刘洪杰 苏建
机构地区 河南周口市中心医院急诊科 河南开封市第一人民医院神经内科
出处 《中国实用神经疾病杂志》 2010年第10期32-33,共2页 Chinese Journal of Practical Nervous Diseases
关键词 施捷因 脑出血 S-100Β蛋白 神经元烯醇化酶 神经损伤 GM-1 Cerebral hemorrhage S-100β protein NSE Neuron injury
分类号 R743.34 [医药卫生—神经病学与精神病学]
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中国实用神经疾病杂志
2010年 第10期

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