高原鼠兔对炔雌醚、左炔诺孕酮和EP-1不育药饵适口性

Palatability of Anti-Fertility Baits Containing Compounds of Quinestrol,Levonorgestrel and EP-1 on Ochotona curzoniae

采用单只饲养方法,选择燕麦(Arena nuda)、颗粒饲料和胡萝卜(Daucus carota)为基饵,分别测定了高原鼠兔(Ochotona curzoniae)对10mg/kg浓度的炔雌醚、左炔诺孕酮和EP-1药饵的适口性。结果表明,高原鼠兔对燕麦和颗粒基饵具有较高的取食偏好性;3种不育成分均未显著改变雄鼠对药饵的适口性;炔雌醚显著降低了雌性高原鼠兔对燕麦药饵的取食量(P=0.0128);但左炔诺孕酮和EP-1均未显著降低高原鼠兔对燕麦、颗粒饵料和胡萝卜药饵的取食量。总之,高原鼠兔对含有10mg/kg浓度3种不育成分的燕麦、颗粒饵料和胡萝卜药饵具有很好的适口性,具有潜在应用前景。

In this study,we investigated the palatability on Plateau Pikas （Ochotona curzoniae） by three baits containing anti-fertility compounds of quinestrol,levonorgestrel and EP-1 （ mixture of the two compounds） respectively with oats （ Arena nuda）,fodder or carrot （ Daucus carota） as baits （ 10 mg /kg）. The results indicated that plateau pikas preferred to eat plain baits of oat and fodder baits over the carrot bait. All the three compounds did not change the palatability of oat,fodder and carrot baits of male pikas. Quinestrol only significantly reduced consumption of oat bait by female Pika （ P = 0. 0128）. Levonorgestrel and EP-1 did not significantly reduced food intake of oat,fodder and carrot baits by pikas. In summary,except quinestrol-oak baits on female pika,all the three anti-fertility compounds showed no significant effect on palatability of Pikas, and thus are promising in fertility control for this species.