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热休克蛋白72在非酒精性脂肪性肝病中的表达及作用 被引量：3

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摘要 近来认为，非感染性炎性应答是非酒精性脂肪性肝病（non-alcoholic fatty liver disease, NAFLD）、糖尿病、高血压等发生发展的重要因素^[1]，内质网应激蛋白可释放至细胞外而作为Toll样受体的内源性配体启动炎性应答^[2]。
作者 黄丹文 晏春根 朱冬芳
机构地区 浙江省绍兴文理学院医学院临床医学系 绍兴文理学院附属医院消化科 绍兴文理学院附属医院检验科
出处 《中华消化杂志》 CAS CSCD 北大核心 2010年第4期268-271,共4页 Chinese Journal of Digestion
关键词 非酒精性脂肪性肝病 热休克蛋白72 TOLL样受体 炎性应答 liver 内源性配体 非感染性 应激蛋白
分类号 R575.5 [医药卫生—消化系统]
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参考文献4

二级参考文献15

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  • 2Fatty Liver and Alcoholic Liver Disease Study Group of the Chinese Liver Disease Association..非酒精性脂肪性肝病诊疗指南[J].中华肝脏病杂志,2006,14(3):161-163. 被引量：1511
  • 3李红,韩德五,张素美,赵龙凤.乙型肝炎患者肠源性内毒素血症、高组胺血症与细胞免疫功能之间的关系[J].中国病理生理杂志,2006,22(3):559-562. 被引量：12
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共引文献3

同被引文献39

  • 1关晓海,陈晶,陈国生,李占清,李晓强.热休克蛋白72的表达对肾移植缺血再灌注损伤的保护及评价意义[J].中国综合临床,2007,23(5):453-455. 被引量：2
  • 2王爱军,曲彦,李敬华.急性创伤患者早期热休克蛋白72的检测及临床意义[J].重庆医学,2007,36(14):1430-1432. 被引量：2
  • 3Farrell GC, van Rooyen D, Gan L, et al. NASH is an Inflammatory Dis- order: Pathogenic, Prognostic and Therapeutic Implications [ J 1. Gut Liver,2012,6(2) :149-171.
  • 4Catalan V, G6mez-Ambrosi J, Rodrtguez A, et al. Increased tenascin C and Toll-like receptor 4 levels in visceral adipose tissue as a link be- tween inflammation and extracellular matrix remodeling in obesity [ J ]. J Clin Endocrinol Metab,2012,97(10) :E1880-1889.
  • 5Gulden E, Ihira M, Ohashi A, et al. Toll-like receptor 4 deficiency ac- celerates the development of insulin-deficient diabetes in non-obese di- abetic mice[Jl. PLoS One,2013,8(9) :e75385.
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  • 10Lawless MW, Greene CM. Toll-like receptor signaling in liver dis- ease : ER stress the missing link [ J ]. Cytokine, 2012,59 ( 2 ) : 195- 202.

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中华消化杂志
2010年 第4期

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