经纤维支气管镜刷检联合活检对痰菌阴性肺结核患者的诊断价值的初步研究

Elementary study on the diagnosis of pulmonary tuberculosis patients with negative sputum specimen by the fiberoptic bronchoscope

目的探讨支气管镜刷检联合活检对痰菌阴性肺结核患者的诊断价值。方法 68例痰菌阴性肺结核患者的治疗前进行支气管镜检查,同时行刷检、活检、刷检联合活检三种方法 ,了解不同方法对肺结核诊断的阳性率。结果活检病例中,阳性率为41.7%,刷检涂片病例中,阳性率为29.2%,刷检联合活检阳性率为62.5%,(P=0.043)。结论经纤维支气管镜刷检联合活检可提高痰菌阴性肺结核患者的阳性诊断率。

Objective To explore the diagnosis value of pulmonary tuberculosis patients with negative sputum specimen by the fiberoptic bronchoscope.Methods 68 cases with negative sputum specimen were checked by the fiberoptic bronchoscope before the treatment,at the same time,the brush examination,biopsy and combination method of brush examination and biopsy were performed respectively,and the positive rate of the diagnosis of the different methods were compared.Results The positive rate of brush examination,biopsy and the combination method were 29.2%,41.7% and 62.5%,respectively.（P=0.043）.ConclusionThe combination method of brush examination and biopsy by the fiberoptic bronchoscope can improve the positive rate of pulmonary tuberculosis patients with negative sputum specimen.