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结直肠癌组织SNX10表达及临床意义 被引量:3

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摘要 目的探讨结直肠癌组织SNX10表达与结直肠癌发生发展的关系。方法应用免疫组化方法 ,检测87例结直肠癌和30例配对正常组织中SNX10表达。结果在结直肠癌组织和配对正常组织中SNX10表达差异有显著性(2=117,P<0.001),癌组织SNX10表达显著低于其相应的正常组织。在结直肠癌组织中,SNX10表达与结直肠癌的分化程度(2=4.805,P<0.05)和浸润深度呈负相关(Z=-5.501,P<0.01),与结直肠癌转移(Z=-1.927,P>0.05)、临床分期(Z=-1.830,P>0.05)等无关。结论 SNX10表达降低可能与肿瘤发生和进展相关。
作者 张伟新 刘莉
出处 《广东医学》 CAS CSCD 北大核心 2010年第9期1173-1174,共2页 Guangdong Medical Journal
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同被引文献19

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