盐酸吡硫醇与硫酸镁在几种输液中的稳定性研究

Stability of Pyritinol Hydrochloride and Magnesinm in Several Transfusions

目的:考察盐酸吡硫醇与硫酸镁在0.9%NaCl、5%GS、5%GNS3种注射液中的稳定性。方法:用上述3种输液配制浓度为0.04%的盐酸吡硫醇溶液,常温下放置0、1、2、6h,观察外观、测定溶液pH及药物含量。结果:盐酸吡硫醇和硫酸镁与上述3种输液配伍,并在常温下放置6h其含量、pH、及外观等均无变化。结论:盐酸吡硫醇与硫酸镁在上述输液中可以配伍。

Objective：Studying the stability of Pyritinol Hydrochloride in 0.9%sodium chloride solution,5%glucose solution,5%glucose and sodium chloride solution.Methods：Using the above three kinds of solvents to make concentrations of 0.04% Pyritinol Hydrochloric solution in 6h during staying at a normal temperature,to observe its appearance,to determine its pH and drug content.Results：There was no change in contents,pH and appearance of the concentrations of pyritinol hydrochloride in above solutions in 6h.Conclusion：Pyritinol hydrochloride and magnesium can be compatible in the transfusion above.