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LPNM促进的C—N键形成反应研究

A novel way to form C-N bond in LPNM media
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摘要 报导了一种新的C—N键的合成方法.以对氯苯胺和芳香仲醇,叔醇作为反应原料,在LPNM(高氯酸锂-硝基甲烷)体系促进下得到C—N键形成产物.该反应所需条件温和,具有一定新颖性. A novel method for carbon-nitrogen bond formation was reported here.Starting from the 4-chlorobenzenamine and aryl secondary and tertiary alcohols as the reactant materials,a series of C-N bond formation product were obtained in the LPNM medium.This reaction proceeded smoothly in moderate condition and thus expressed its novelty.
出处 《苏州大学学报(自然科学版)》 CAS 2010年第2期84-86,共3页 Journal of Soochow University(Natural Science Edition)
关键词 LPNM C—N键 亲核反应 LPNM C—N bond nucleophilic reaction
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参考文献13

  • 1Lawrence S A.Amines:synthesis,properties and applications[M].Cambridge:Cambridge University Press,2005.
  • 2Zbinden K G,Banner D W,Ackermann J D.Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors[J].Bioorg Med Chem Lett,2005,15(3):817-822.
  • 3Smith M B,March J.Advanced Organic Chemistry[M].New York:Wiley,2001:499.
  • 4Ralph N S,Cheol H Y,Kyung W J.Synthesis of secondary amines[J].Tetrahedron,2001,57:7785-7811.
  • 5Watanabe Y,Tsuji Y,Ohsugi Y.The ruthenium catalyzed N-alkylation and N-heterocyclization of aniline using alcohols and aldehydes[J].Tetrahedron Lett,1981,22:2667.
  • 6Blank B,Michlik S,Kempe R.Selective Iridium-catalyzed alkylation of(hetero)aromatic amines and diamines with alcohols under mild reaction conditions[J].Chem European J,2009,15:3790-3799.
  • 7Zhu Z L,Espenson J H.Organic reactions catalyzed by methylrhenium trioxide:dehydration,amination,and disproportionation of alcohols[J].J Org Chem,61:324-328.
  • 8Gunanathan C,Milstein D.Selective synthesis of primary amines directly from alcohols and ammonia[J].Angew Chem Int Ed,2008,47:8661-8664.
  • 9Wang G W,Shen Y B,Wu X L.Phosphotungstis acid catalyzed amidation of alcohols[J].Eur J Org Chem,2008,4367-4371.
  • 10Terrasson V,Marque S,Georgy M,et al.Lewis acid-catalyzed direct amination of benzhydryl alcohols[J].Adv Synth Catal 2006,348:2063-2067.

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