射频消融术治疗乳腺良性病变的形态学观察

RADIOFREQUENCY ABLATION OF BENIGN BREAST LESIONS MORPHOLOGICAL OBSERVATION

目的：观察哺乳期伴妊娠羊乳腺组织射频治疗后的形态学变化并评价其应用价值。方法：对2只哺乳期伴妊娠山羊乳腺组织进行射频消融治疗，消融温度90℃-100℃，常规手术时间25min，范围直径1cm。治疗后分2组，分别于术后即刻、术后3个月进行超声检查，并处死，行内眼观察和组织病理学检查。结果：术后即刻消融灶距离皮肤表面1cm、距离基底部1cm。肉眼观察呈灰暗色约1．5cm×1．5cm×1．5cm，切片见乳腺小叶萎缩，乳管扩张，细胞分泌功能减退，间质充血及少许炎细胞浸润。术后3个月消融区切面灰白，乳池内见窦状胶冻区。显微镜下乳腺小叶萎缩，乳管扩张。

Objective： Evaluation of value and morphological changes in lactating mammary glang tissue of pregnant goat after radiofrequency ablation（RFA） treatment. Method：Pairs of lactating mammary gland of pregnant goat underwent radiofrequency ablation , abla- Lion temperature of 90℃ - 100 ℃, normal operation time 25min, range of diameter of 1 cm. Respectively, divided into 2 groups after operations,one group which was executed immediately , then was given uhrasound examination , observation by unaided eye and histopathological examination, another was executed after 3 months which underwent the same examinations. Result ： Distance of ablation lesions of immediate group was lcm from skin surface,lcm from the base. Gray - dark lesion was about 1.5 ＊ 1.5 ＊ 1.5cm. The changes under microscope were like lobular atrophy, duet expansion, cell secretion dysfunction, interstitial congestion and a litde inflammatory cell infiltration as so. Conclusion ： The damage of radiofrequency ablation on lactating goat mammary tissue is not obvious.