低能量氦氖激光照射对荷瘤小鼠NK细胞活性的影响

Effect of Low-energy He-Ne Laser lrradition on the NK Activity of S 180 -Bearing Mouse

研究低能量氦氖激光照射荷瘤小鼠对ＮＫ细胞活性的影响。选取ＢＡＬＢ／Ｃ雄性小鼠腹腔接种Ｓ１８０，接种后进行激光照射小鼠内眼角，监测了正常对照组、肿瘤对照组和７．３３、１１．００、１４．６７、２２．００、２９．３３Ｊ／ｃｍ２五个激光照射组能明显提高荷瘤小鼠ＮＫ细胞活性（Ｐ＜０．０１）；７．３３、２９．３３Ｊ／ｃｍ２照射组则升高不明显。

The effects of low-energy He-Ne laser irradition on NK activity were systematically studied in the present study afterinoculation S 180 .Five groups of BALB/C mice were irradited at the spot of inner corner of the mouse eye for six days with five different doasages such as 7.33,11.00,14.67,22.00 and 29.33 J/cm 2.After inoculation S 180 sarcoma cells,the NK actitity were monitored kinetically by killing 5 mice in each group at the 4 th,8 th and 12 th day after irradiation.The results showd that the low-energy He-Ne laser irradition of 7.33,11.00,14.67 and 22.00 J/cm 2 could increase the NK activity in some degree.In the opposite direction,the results also show that large doasage of 29.33 J/cm 2 low energy laser irradition could decrease the NK activity.(009)