蜘蛛香的化学成分研究

Studies on chemical constituents of Valeriana jatamansi

目的:研究蜘蛛香Valeriana jatamansi的化学成分。方法:通过各种色谱手段(Silica gel、ODS、HPLC)对蜘蛛香甲醇提取物进行分离纯化,通过1H-NMR、13C-NMR等波谱技术确定化合物的结构。结果:分离并鉴定了4个含氯元素的环烯醚萜类化合物,分别为rupesin B(1)、chlorovaltrate(2)、volvaltrates B(3)、1,5-dihydroxy-3,8-epoxyvalechlorine A(4)。结论:化合物1～3为首次从植物蜘蛛香中分离得到。

Objective： To investigate the chemical constituents from the seeds of Valerianajatamansi. Methods： The compounds were isolated by chromatography and identified on the basis of physico-chemical constants and spectral analysis. Results： Four iridoid compounds were isolated and their structures were identified as rupesi B （1）, chlorovaltrate （2）, volvaltrates B （3）, 1, 5-dihydroxy-3, 8-epoxyvalechlorine A （4）. Conelusion： Compounds 1-3 are isolated from this plant for the first time.