奥美拉唑三联疗法配合针灸治疗胃溃疡60例疗效观察

TRIGEMINY THERAPY AND ACUPUNTURE IN TREATING 60 CASES OF GASTRIC ULCER

目的研究奥美拉唑、羟氨苄青霉素、甲硝唑三联疗法配合针灸治疗胃溃疡的临床疗效。方法将120例经胃镜及病理证实为胃溃疡患者,随机分为观察组60例和对照组60例。2组均给予三联疗法治疗,观察组同时给予针刺中脘、内关、足三里穴治疗,治疗时间均为2周。结果治疗1周后上腹痛消失时间观察组为(0.7±1.2)d,对照组为(2.5±1.3)d,两组比较有显著性差异(P<0.01)。治疗6周后临床症状积分观察组为(30.5+2.1)分,对照组为(48.6+2.9)分,两组比较有显著性差异(P<0.05);观察组和对照组的溃疡愈合率分别为93.3%和66.7%,两组比较有显著性差异(P<0.05)。疗程结束后4周,Hp根除率观察组为93.3%,对照组为81.7%,两组比较有显著性差异(P<0.05)。结论奥美拉唑三联疗法配合针灸治疗胃溃疡具有缓解临床症状快,止痛效果好,溃疡的愈合率、治愈率高和Hp根除率高等优点,值得推广应用。

Objective To explore the curative effects of trigemity with omeprazole, amoxicillin and metronidazole and acupuncture on gastric ulcer. Methods The 120 pathologically-confirmed gastric ulcer were randomly divided into the observation group of 60 cases and the control group of 60 cases. Both groups were treated with trigeminy therapy, but the observation group were simultaneously given acupuncture at the positions of chungwan, nei kuan and tsusanli. Results After one week of treatment, upper abdominal pain vanished in （0.7±1.2） days in the observation group,and （2.5 ± 1.3）days in the control group （ P 〈0.01）. After 6 weeks of treatment, the clinical symptoms showed （30.5 ± 2.1 ） integral points in the observation group, and （48.6 ± 2.9） integral points in the control group （ P 〈0.05）. The healing rates in the observation group and the control group were 93.3% and 66.7% respectively（ P 〈0.05）. The helicobaeter pylori （HP） eradication rate after 4 weeks of treatment was 93.3% in the observation group and 81.7% in the control group （ P 〈0.05）. Conclusion Trigemity with omeprazole, amoxicillin and metronidazole and acupuncture can produce good curative effects on gastric ulcer.