5KANZAWA T, ZHANG L, XIAO L, et al. Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3 [ J ]. Oncogene, 2005, 24(6): 980-991.
6ESHLEMAN JS, CARLSON BL, MLADEK AC, et al. Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy [ J ]. Cancer Res, 2002, 62 ( 24 ) : 7291-7297.
7CANUDAS A M, JORD E G, VERDAGUER E, et al. Cyclo-sporin A enhances colchicine-indueed apoptosis in rat eerebellar granule neurons[ J]. Br J Pharmacol, 2004, 141 (4) : 661-669.
8NAKAHARA C, NAKAMURA K, YAMANAKA N, et al, Cyclosporin-A enhances docetaxel-induced poptosis through inhibition of nuclear factor-kappaB activation in human gastric carcinoma cells [J]. Clin Cancer Res, 2003, 9(14) : 5409-5416.
9ZUPANSKA A, DZIEMBOWSKA M, ELLERT-MIKLASZEWSKA A, et al. Cyclospofine a induces growth arrest or programmed cell death of human glioma cells [ J ]. Neurochem lnt, 2005, 47 (6) : 430-441.
10CHEN G Q, ZHU J, SHI X G, et al. In vitro studies on cellular and molecular mechanisms of arsenic trioxide( As2O3 ) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins [ J ]. Blood, 1996, 88 ( 3 ) : 1052-1061.
5Toso C, Merani S, Bigam DL, et al. Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellu- lar carcinoma. Hepatology,2010;51: 1237 - 1243.
6Miracco C , Cosci E , Oliveri G, et al. Protein and mRNAex2 pression of autophagy gene Beclin 1 in human brain tumours. Int J Oncol , 2007 ;30 : 429 - 436.
7Wang ZH, Xu L, Dural ZL, et al. Beelin 1-mediated maereau toph-y involves regulation of easpase-9 expression in cervical cancer HeLa cells. Gy- neeol Oneol, 2007 ;107: 107 - 113.
8Maiufi MC, Criollo A, Tasdemir E, et al. BH3-only proteins and BH3 mimctics induce autophagy by competitively disrupting the interaction between Beclin I and Bet22- Bcl2X. Autophagy,2007 ;3 : 374 -376.
9Mcijcr AJ , Codogno P. Regulation and role of autophagy in mammalian cells. Int J Biocbem Cell Biol , 2004;36:2445 -2462.
10Kimura S, Fujita N, Noda T, et al. Monitoring autophagy inmammalian cultured cells through the dynamics of LC3. Methods Enzymol, 2009 ; 452: 1 -12.
