间断蓝光加金双歧治疗新生儿高胆红素血症疗效观察

目的探讨蓝光加金双歧对新生儿高胆红素血症的治疗效果,以指导临床工作。方法将196例新生儿高胆红素血症患儿随机分成两组,观察组98例,对照组98例,2组在性别、日龄、体重、黄疸病因及程度方面相比较,无显著差异,具有可比性。对照组使用肝酶诱导剂、白蛋白、茵枝黄及蓝光连续照射治疗、口服金双歧治疗。观察组使用肝酶诱导剂、白蛋白、茵枝黄及蓝光间断照射治疗、口服金双歧治疗。结果观察组患儿治疗24h后胆红素值(258.6±35.6)μmol/L,48h为(212.5±35.6)μmol/L,72h为(192.8±34.1)μmol/L,黄疸消退情况:平均每2.9天降至标准以下。与对照组相比较,24、48、72h胆红素值及退黄时间有显著性差异(t=2.73,3.73,2.71,5.94;P<0.05)。结论间断蓝光照射加金双歧治疗新生儿高胆红素血症,效果良好。

Objective To blue-light add gold bifid of neonatal hyperbilirubinemia occurs normally,in order to guide the therapeutic effect of clinical work.Methods 196 newborns hyperbilirubinemia occurs were randomly divided into two groups,the Observer Group 98 cases,the Control Group 98 cases,two groups in gender,age,weight,the etiology and degree of jaundice,no significant difference compared,comparable.YouDaoJi lier enzymes in use,albumin,yellow and blue wormwood branch continuous radiation therapy,oral gold cl.perfringen treatment.The observation group using lier enzymes YouDaoJi,albumin,yellow and blue wormwood branch intermittent radiation therapy,oral gold cl.perfringen treatment.Results the observation group with 24hours after treatment（258.6±35.6）μmol/L maximum tire-road friction coefficient value bilirubin mol/l,48 hours for maximum tire-road friction coefficient 212.5±35.6μmol/L,72 hours for（192.8±34.1）μmol/L,pavement condition：average each presented below the standard to 2.9 heaven.Compared with controls,24,48,72 hours bilirubin value and retreat yellow time have significant difference（t=2.73,3.73,2.71,5.94;P0.05）.Conclusion with golden light irradiation intermittent cl.perfringen in the treatment of neonatal hyperbilirubinemia occurs,the effect is good.