自拟补肾益气清络汤治疗慢性肾小球肾炎的临床观察

Clinical observation on the treatment of chronic glomerulonephritis with Bushen Yiqi Qingluo decoction

目的 探讨补肾益气清络汤对慢性肾小球肾炎的临床疗效.方法 84例患者随机分成两组,对照组予西药治疗,治疗组在对照组基础上加用补肾益气清络汤治疗,观察两组疗效及实验室指标的变化.结果 治疗组总有效率为90.48%,对照组为76.19%,差异有统计学意义（χ2=4.867〉3.840,P〈0.05）;治疗组治疗后尿蛋白定量、血清肌酐及尿素氮水甲较对照组治疗后及本组治疗前明显降低,内生肌酐清除率明显升高（P均〈0.05）.结论 自拟补肾益气清络汤结合西医治疗慢性肾小球肾炎有确切疗效.

Objective To observe the efficacy of Bushen Yiqi Qingluo decoction treating chronic glomerulonephritis. Methods 84 patients were randomly recruited into a control group and a treatment group. The control group was treated with western medicine; while the treatment group was treated with Bushen Yiqi Qingluo decoction based on the control group. The efficacy and the change of lab indexes were observed. Results The total effective rate was 90.48% and 76.19% in the treatment group and the control group respectively, showing significant difference （P〈0.05） . After the treatment, the levels of urinary protein, Scr, and BUN in the treatment group were significantly decreased compared with the control group and the levels before the treatment. The levels of Ccr were increased significantly. Conclusion Bushen Yiqi Qingluo decoction Combined with basic western medical treatment was effective in treating chronic glomerulonephritis.