动脉置入导管化疗后二期切除治疗晚期直肠癌

Therapy of secondary operation on advanced rectal cancer after chemotherapy by indwelling catheter in artery

目的探讨晚期直肠癌动脉栓塞化疗后二期切除的远期疗效。方法对９６例不能手术根治切除的晚期直肠癌行髂内动脉、直肠上动脉置管栓塞化疗，对其中部分缓解且无远处或局部广泛转移的３１例进行二期切除。结果获随访２９例，死亡８例，２１例健在，其中无癌生存１６例，１，３，５年生存率（寿命表法）分别为９３０％，７８０％，７０８％。结论髂内动脉、直肠上动脉置管栓塞化疗后二期切除晚期直肠癌，提高了根治性切除率和远期疗效。

Objective In order to investigate the long term result of secondary operation on advanced rectal cancer after arterial embolism chemotherapy. Methods We treated 96 patients, who couldn't be radically operated on with arterial embolism chemotherapy by indwelling catheter in internal iliac artery and superior rectal artery. Of them 31 cases who had partial remission and without local or distant metastasis were treated with secondary operation. Results Twenty nine patients were followed up, 8 cases died; 21 cases still alive, of whom 16 cases were cancer free. The survival rates of one year, three year and fiver year were 93.0%, 78.0%, 70.8% respectively. Conclusions In patients with advanced rectal cancer after arterial embolism chemotherapy by indwelling catheter in internal iliac artery and superior rectal artery, secondary operation can be performed on some selective patients to improve the rate of radical operation and the long term result.