摘要
为观察静脉化疗及腹腔化疗对细胞免疫的影响，选择较好的化疗方案，自１９９４年起，连续对１８例大肠癌根治术后早期静脉化疗及２１例腹腔化疗病人进行观察，行５－Ｆｕ加左旋咪唑方案化疗。通过化疗前后抽血检查Ｔ细胞亚群比例及ＮＫ细胞比例的变化，发现腹腔化疗组上述指标无明显下降，静脉化疗组下降明显，证明腹腔化疗对细胞免疫抑制较重。
The effects of intraperitoneal chemotherapy on cell-mediated immunity were compared and the more effective method was identified.Eighteen patients were treated with intravenous chemotherapy and 21 patients were treated with intraperitoneal chemotherapy.5-Fu and Levamisole were administered.The ratio of subgroup T cells and NK cells was determined using haemospasia before and after chemotherapy.It was discovered that the ratio declined less in the intraperitoneal cases than in the intravenous cases.This indicates that cell-mediated immunity is depressed to a lesser degree after intraperitoneal chemotherapy.Intraperitoneal chemotherapy is a more effective adjuvant treatment for postoperative colorectal cancer patients.
出处
《中国现代医学杂志》
CAS
CSCD
1999年第2期8-9,共2页
China Journal of Modern Medicine
关键词
大肠癌
腹腔化疗
静脉化疗
细胞免疫
Colorectal cancer
Intraperitoneal chemotherapy
Intravenous chemotherapy
Cellmediated immunity
