三联法治疗大学生肠易激惹综合征临床疗效观察

Clinical observation on triple therapy for irritable bowel syndrome in college students

目的:探讨丽珠肠乐胶囊、得舒特联合抗抑郁药物阿米替林三联法治疗大学生肠易激惹综合征的临床疗效。方法:将41例肠易激惹大学生患者随机分为两组,治疗组21例,用丽珠肠乐胶囊、得舒特联合抗抑郁药物阿米替林三联法治疗;对照组20例,单纯采用丽珠肠乐胶囊及得舒特治疗,4周后进行疗效评价。结果:治疗组显效14例,有效6例,无效1例,总有效率为95%,疗效优于对照组总有效率(65%)(P<0.05)。结论:采用丽珠肠乐胶囊、得舒特联合抗抑郁药物阿米替林三联法治疗大学生肠易激惹综合征的疗效确切,值得临床推广应用。

Objective：To investigate the clinical efficacy for Irritable Bowel Syndrome（IBS） of college students with Bifidobacterium Capsule,Dicetel and antidepressants of Amitriptyline. Methods：41 IBS patients were randomly divided into two groups：therapy group（21 cases） and comparison group（20 cases） . In the treatment group,patients were treated with Bifidobacterium Capsule,Dicetel and Amitriptyline;in the control group,patients were simply treated with Bifidobacterium Capsule and Dicetel. And evaluations were collected after 4 weeks. Results：In treatment group,14 cases were excellent,6 cases were effective,and only 1 patient was inefective,the total effective rate was up to 95%,which was much more effective than that of comparison group（65%） （P〈0.05） . Conclusion：Triple therapy with Bifidobacterium Capsule,Dicetel and Amitriptyline for IBS in college students is effectively feasible,it＇s worthy of clinical use.