盐酸利托君治疗前置胎盘的疗效观察

Efficacy on Ritodrine Hydrochloride for placenta previa

目的:探讨盐酸利托君在前置胎盘治疗中的临床疗效。方法:对50例使用盐酸利托君和50例使用硫酸镁的前置胎盘患者进行回顾性临床分析,对用药后的阴道出血情况、治疗效果、妊娠结局和不良反应进行比较。结果:利托君组的保胎成功率、显效时间、延长孕周、妊娠期≥36周比率均明显优于硫酸镁组,且两组间差异均有统计学意义(P<0.05);两组阴道出血、产后出血情况和围生儿结局无明显差别(P>0.05);盐酸利托君和硫酸镁有不同的药品不良反应。结论:盐酸利托君抑制宫缩效果优于硫酸镁,是治疗前置胎盘的一种有效药物。

Objective：To evaluate the clinical efficacy of Ritodrine Hydrochloride for placenta previa. Methods：50 patients with placenta previa treated with Ritodrine Hydrochloride and 50 patients with placenta previa treated with Magnesium Sulfate were analyzed retrospectively. The colporrhagia,therapeutic efficacy,pregnancy outcome and the adverse effect were compared after medication. Results：Compared with Magnesium Sulfate group,there was a significantly higher proportion of achievement ratio of tocolysis,reactive time,extension of pregnancy period and rate of gestation period over 36 weeks in Ritodrine Hydrochloride group（P〈0.05） . There was no differences between the two groups in colporrhagia,postpartum hemorrha and perinatal outcome（P〉0.05） . The two drugs had different adverse drug reactions. Conclusion：Ritodrine Hydrochloride is better than Magnesium Sulfate on inhibiting uterine contraction. It is an effective drug in treating placenta previa.