关于动脉粥样硬化发病机制的探讨

Research on the pathogenesis of atherosclerosis.

动脉粥样硬化是心血管疾病中最常见的疾病，也是危害人类健康的常见病。AS主要累及大中动脉，基本病变是动脉内膜的脂质沉积，内膜灶状纤维化，粥样斑块形成，致管壁变硬、管腔狭窄，并引起一系列继发性病变，特别是发生在心、脑、肾等器官，可引起缺血性病变。AS的发病机制尚未最后阐明，现将综合各学说对AS的发病机制作一阐述。

Atherosclerosis （AS） is common among cardiovascular system disease. AS is a degenerative disease of large and medium sized arteries characterized by lipid deposition and fibrosis, then contribute to atheromatous or fibrofatty plaques , that protrude into and obstruct vascular canal, waken the underlying media, and may undergo serious complications, especially in heart, brain and kidney.