氯诺昔康与丁丙诺啡术后镇痛效果比较

Comparison of postoperative analgesia between lornoxicam and buprenorphine

目的 比较氯诺昔康和丁丙诺啡的术后镇痛效果及不良反应.方法 60例ASA Ⅰ-Ⅱ级患者,随机分为两组：氯诺昔康A组（n=30）和丁丙诺啡B组（n=30）,两组均通过电子泵经皮下给药.采用视觉模拟评分法（VAS）测定患者的术后镇痛效果,记录不良反应.结果 两组患者的性别、年龄、身高、手术类型和麻醉方法等一般情况差异无统计学意义（P〉0.05）.两组的术后镇痛效果和不良反应的指标均差异无统计学意义（P〉0.05）.结论 在术后患者自控镇痛中,氯诺昔康因其与丁丙诺啡相似的镇痛效果且无呼吸抑制的优点可以作为丁丙诺啡的替代用药.

Objective To study the efficacy arid side effects of postoperative analgesia between Lornoxicam and Buprenorphine. Methods Sixty ASA I-II patients were randomly divided into Lomoxicam group（group A） and Buprenorphine group（group B）. Analgesiae were subcutaneously injected via an electronic patients controlled analgesic pump post surgeries. The visual analgesiae sacle（ VAS） was used to evaluate the postoperative pain relief,and analgesic response was recorded. Result There were no significant differences between Lomoxicam and Buprenorphine about the analgesic response（P〉0. 05）,moreover,no stastical differences in the patients demography,analgesic and anesthetic type were associated with the analgestic outcomes. Conclusion Lomoxicam without respiratory distuber-ance was a good alternative to Buprenorphine in PCSA.