急性出血性坏死性胰腺炎外科干预的时机与预后分析

Timing of surgical treatment and prognosis in patients with acute hemorrhagic necrotizing pancreatitis

目的:探讨急性出血性坏死性胰腺炎(AHNP)外科干预的时机与预后分析。方法:回顾性分析46例AHNP患者的外科干预时机选择与并发症发生率、病死率和再手术率等资料。结果:早期手术组、延期手术组和非手术组的并发症发生率分别为70%(7例)、33%(7例)、33%(5例)。早期手术组较后两组差异有显著性(P<0.05);而病死率分别是40%(4例)、10%(2例)、13%(2例),早期手术组明显高于后两组(P<0.05)。早期手术组再手术率为90%,而延期手术组再手术率为19%(P<0.01)。结论:正确把握AHNP的外科干预的时机,对AHNP预后是至关重要的因素。

Objective：To study the timing of surgical treatment and prognosis in the patients with acute hemorrhagic necrotizing pancreatitis（AHNP）.Methods：The timing of surgical intervention,surgical complications,mortality and reoperation rate were reviewed in 46 cases with AHNP in our hospital from January 1999 to July 2009.Results：The complication rates of early,late stage and that of nonoperation group were respectively 70%,33% and 33%.respectively（P0.05）.Their mortalities were respectively 40%,10% and 13%,respectively（P0.05）.The reoperation rates in early and late stage groups were 90% and 19% respectively（P0.01）.Conclusion：Appropriate choice of the timing of surgical interventiom is vital to the prognosis of AHN.