阿苯达唑联合吡喹酮治疗脑囊虫病的临床疗效观察

Clinical Observation on albendazole combined with praziquantel treatment of neurocysticercosis

目的：探讨阿苯达唑与吡喹酮联合应用治疗脑囊虫病的临床疗效。方法：随机将脑囊虫病患者分为观察组和对照组。对两组患者的治愈率、显效率、无效率、总有效率及毒副反应等进行对比分析。结果：与对照组相比，观察组患者服药后的治愈率和总有效率均明显上升，且观察组患者服药后的头痛和发热症状均明显降低，差别均具有统计学意义（P〈0．05）。结论：阿苯达唑与吡喹酮联合应用可以有效治疗脑囊虫疾病。且毒副作用小，具有十分重要的临床意义。

Objective： To probe into the clinical effect of the combination of albendazole and praziquantel treatment of neurecysticereosis. Methods： Neuroeystieercosis patients were divided into observer group and control group randomly. Comparative analysis the patients of cure rate, markedly effective, inefficiencies, the total effective rate and toxicity in the two groups. Results： Compared with control group, observer group after taking the cure rate of patients and the total efficiency was increased, and the observer group after medication in patients with symptoms of headache and fever were reduced, there were significant differences （P 〈0.05）. Conclusions： Albendazole and praziquantel in combination can be effectively treated disease, neurocysticercosis, and toxic side effects of great clinical significance.