医疗机构与结防机构对初治涂阳肺结核病人不同化疗方案的治疗效果评价

The Medical establishment with ties against organization to initially to govern spreads positive pulmonary tuberculosis patient the different chemotherapy plan the treatment result to appraise

目的：探讨肺结核初治涂阳患者采用不同化疗方案治疗的效果比较。方法：总结了2005年1月至2006年12月湖南省结核病医院采用2HRZEV／THR治疗的初治涂阳病人中随即抽取53例（A组）和同期岳麓区疾控中心予2H3R3E323／4心凡治疗的初治涂阳病人88例（B组）在治疗中和治疗末的效果。结果：A组与B组比，两组在治愈率和复发率方面存在显著性差异，（A组治愈率优于B组，复发率低于B组），但在两组2月末阴转率及肝功能损害方面无统计学意义。结论：同期医院正规抗结核治疗9个月，其5、6月末阴转率、治愈率高于结防机构6个月规则治疗，复发率低于结防机构6个月规则治疗。

Objective Discussion pulmonary tuberculosis initially governs spreads the positive patient to use the different chemotherapy plan treatment the effect comparison. Methods Summarizes January, 2005 Hunan Province tuberculosis hospital to use the 2HRZEV/7HR treatment to December, 2006 initially to govern spreads in the positive patient to extract 53 examples immediately （ A group） and the same time Yuelu District CSC gives the 2H3R3E3Z3/4H3R3 treat- ment initially to govern spreads the positive patient 88 examples （B group） in the treatment neutral treatment end effect. Resuts A group with B group compared to, two groups has the unusual significance difference in the cure rate and the recurrence rate aspect （A group to surpass B group）, but in two group in the end of February cloudy rate of rotation liver function harm aspect non - statistics significance. Conclusion Same time the hospital regular anti - tuberculosis treats 9 month its 5, at the end of June cloudy rate of rotation, the cure rate and the recurrence rate is higher than ties against organization 6 month rule treatment, the former is worth promoting.