摘要
目的：观察应用依达拉奉注射液治疗急性脑梗死的临床疗效及安全性.方法：选择发病72h内的急性脑梗死患者160例,随机分为治疗组80例和对照组80例.对照组采取常规药物治疗,包括静点丹参、血塞通等改善脑循环药物,并口服阿司匹林.治疗组在常规治疗的基础上再用依达拉奉注射液治疗,一次30mg,每日2次,14d为一个疗程.治疗前后进行神经功能缺损评分和日常生活能力评分（Barthel指数）.结果：治疗后两组均能降低神经功能缺损评分,提高Barthel指数,但是治疗组疗效显著优于对照组.依达拉奉注射液治疗过程中无不良反应发生.结论：在常规用药基础上加用依达拉奉注射液治疗急性脑梗死有较好的疗效和安全性,值得推广.
Objective, To observe the efficacy and safety of edaravone injection on the treatment of acute stroke patients. Methods： 160 patients with the onset of symptoms in 72 hours were divided into treatment group and control group. The control group was treated with salvia miltiorrhiza, xuesaitong injection and aspirin etc. The treatment group was treated with edaravone injection of 30 mg/bid for 2 weeks and with salvia miltiorrhiza, xuesaitong injection and aspirin etc as well. The efficacy and safety were evaluated with neurological deficit score, Barthel score and side effects. Results：The neurological deficit score was significantly reduced both in treatment group or control group. The Barthel score was significantly increased both in treatment group or control group. The efficacy of the treatment group was much better than the control group. No side effects were observed in the treatment group. Conclusion： Edaravone injection is an effective and safe drug for the treatment of acute stroke.
